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Trio-Salice Cream is a topical treatment formulated for oily and acne-prone skin. According to product listings, its key active ingredients include:

Salicylic acid ~2% — a keratolytic and pore-clearing agent.
Niacin (nicotinamide) ~4% — reported to reduce inflammation and redness.
Calendula extract ~5% — a botanical used for its soothing and antiseptic-ish properties.
Other supportive ingredients (e.g., white tea extract) in small amounts.

The product is described as treating blackheads and whiteheads, unclogging pores, controlling oil production, and helping prevent new blemishes.

How it works (mechanism)

Salicylic acid: This is a beta‐hydroxy acid (BHA) that penetrates into pores and helps exfoliate inside the pore lining, which can loosen and remove comedones (blackheads/whiteheads) and prevent further clogging. The product listing notes salicylic acid is “anti‐inflammatory, keratolytic, anti‐fungal and anti‐bacterial.”
Niacin (vitamin B3): Known to help with redness, skin barrier function and potentially sebum regulation (though effects may vary) — here it seems included to manage inflammation and visible signs of acne.
Calendula & White Tea Extract: These serve more for soothing, antioxidant, and calming support rather than direct acne-clearing. The inclusion suggests the formulation tries to balance exfoliation with soothing to reduce irritation.

Intended Uses & Benefits

For individuals with oily or combination skin, especially those who struggle with blackheads/whiteheads (closed or open comedones) and clogged pores.
As a night treatment (some listings say apply at night) to help clear pores before the skin rests.
As part of an acne-management routine: helps prevent new breakouts by reducing pore-clogging and controlling oil.
For skin that tolerates exfoliants and actives well (since salicylic acid at ~2% is moderate strength).

How to Use It

On clean, dry skin, apply a thin layer of Trio-Salice Cream to affected areas (i.e., areas prone to blemishes, clogged pores).
Use once or twice daily, depending on how your skin tolerates it. (The listing says once or twice daily depending on tolerance.)
Avoid sensitive areas (e.g., around the eyes, broken skin).
Follow with a moisturiser if needed, especially since exfoliants may dry out skin.
Use sun protection daily (SPF) because even though salicylic acid is less photosensitizing than some acids, when you use exfoliants your skin may be more vulnerable to sun damage.
If using other strong actives (like retinoids, other acids), introduce slowly to avoid over-irritation.

Who Should & Shouldn’t Use It

Good fit:

Those with oily skin, visible clogged pores, blackheads/whiteheads.
Those who already use gentle exfoliants and are tolerating them well.
People looking for maintenance of acne-prone skin, not necessarily very inflamed cystic acne (though could help).

Be cautious / avoid:

Very sensitive skin, rosacea-prone skin, or skin that easily irritates — salicylic acid still may cause dryness or stinging.
If using strong prescription treatments (like high-dose retinoids, benzoyl peroxide) without guidance.
If you have broken skin, eczema flare-ups, or open wounds — avoid applying until healed.
Pregnant or breastfeeding? Salicylic acid topical use is generally considered safe in low doses but always check with a healthcare professional.

Potential Side Effects & Tips

Mild tingling or a bit of dryness/peeling is possible as the exfoliant works.
If you experience excessive stinging, redness, or irritation, reduce frequency (e.g., every other night) or stop and consult a dermatologist.
Patch test recommended: apply on a small area (e.g., jawline) for a few nights and monitor.
Because it helps unclog pores, purge effect (small breakout) may happen initially — but differentiate between “purge” and irritation; if irritation persists, stop.
Keep moisturiser and sunscreen part of your routine — exfoliants alone can stress the skin barrier.